| Raleigh, North Carolina – April 7, 2009 – | | | | Current and Future Manufacturing Platforms,” the |
| Ajinomoto AminoScience, LLC, announced the launch | | | | firm outlines the need for advances in manufacturing. |
| of Corynex™ Recombinant Protein Expression | | | | The study describes a “reluctance” by |
| System, ( a streamlined, more efficient process to | | | | companies to modernize with new technology and |
| express proteins. The breakthrough, patented | | | | methodologies so products can be made “more |
| system overcomes traditional microbial expression | | | | efficiently and to higher clinical standards.” |
| difficulties by secreting correctly folded, active | | | | “This new process shows Ajinomoto’s |
| proteins directly into the growth media. This system | | | | willingness to invest in scientific efforts to improve |
| eliminates costly and time consuming downstream | | | | expression systems,” says Heaton. “We |
| purification steps which reduce production costs and | | | | have answered the industry’s call to develop |
| accelerate speed to market for Ajinomoto’s | | | | better technology to meet our customers’ |
| pharmaceutical and biotech partners. | | | | needs.” |
| “Ajinomoto’s innovative Corynex ™ | | | | Ajinomoto, the worlds’ largest manufacturer of |
| Recombinant Protein Expression System reinforces | | | | amino acids, was the first company in the world to |
| 50 years of leadership within the fermentation and | | | | identify, refine and market amino acids. The |
| expression fields,” says Jack Heaton, president of | | | | company is considered the leader in pioneering new |
| Ajinomoto AminoScience, LLC. “With the debut | | | | technologies and research and development of amino |
| of our new system, we demonstrate that Ajinomoto | | | | acids. The Raleigh, North Carolina facility, which began |
| is an unrivaled industry leader.” | | | | production in 1982, is the only U.S. manufacturer of |
| This advanced technology is Ajinomoto’s answer | | | | cGMP pharmaceutical grade amino acids. Key |
| to a recent analysis of biotechnology manufacturing | | | | applications include use in therapeutic pharmaceutical |
| by BioPlan Associates, a biotechnology marketing | | | | development, cell culture media, parenteral and clinical |
| research firm in Rockville, Maryland. In the January | | | | nutrition, health foods and food applications. |
| 2009 study entitled “Genetic Expression Systems: | | | | |