Bird Flu: Why Modern Medicine Won

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Very often when people begin to learn about bird flu,everyone.
they jump to the conclusion that because medicineVaccines, like antiviral medicines, are not 100 percent
has advanced by quantum leaps since the 1918-19effective in either preventing infection or minimizing
influenza pandemic (global epidemic), there is nothingsymptoms once infected. A startling new report (a)
to worry about. They are certainly right about thefound only limited benefit from influenza vaccines:
advance of medicine, which has been extraordinary“In people over 65, the vaccines ‘are
by any measure. Unfortunately, when it comes toapparently ineffective’ in the prevention of
dealing with a bird-flu pandemic, these advances fallinfluenza, pneumonia and hospital admissions, although
short in many areas. To name the most significant:they did reduce deaths from pneumonia a bit, by up
1. Bird flu is caused by an influenza virus, for whichto 30 percent.”
there are only four approved antiviral agents in theAccording to the Influenza Vaccine Supply (IVS)
U.S. The virus has extensive resistance to two ofInternational Task Force, “Whatever scenario,
these medicines already, and resistance mighteven the most optimistic, the worldwide [vaccine]
develop in the remaining two once they are usedproduction capacity will be clearly insufficient in case
more widely in a pandemic. The two remainingof pandemic.”
medicines, Tamiflu (oseltamivir) and Relenza7. Shortages of nurses and other healthcare
(zanamivir), are in extremely short supply and, evenpersonnel will be significant, because of overexposure
with planned increases in their manufacture, willto people with bird flu—and thus a higher illness
remain in short supply for many years to come.and death rate among healthcare workers, and
These medicines must be given within 48 hours ofbecause a high proportion will simply decide not to
the onset of symptoms, which can be difficult tocome to work. A similar situation occurred in New
accomplish for a variety of reasons. Even when theyOrleans during Hurricane Katrina when 250 members
are available and given on time, their effectiveness isof the police department (one-sixth of the force)
less than 100 percent. And because bird flu is veryabandoned their jobs during the hurricane and
different than the usual influenza we are used to,flooding. It also happened in Toronto during the SARS
higher doses given for longer periods of time may beoutbreak, when some nurses and other healthcare
necessary for optimal effect.workers submitted their resignations (although many
2. While we have many wonderful antibioticwere persuaded to stay).
medicines, these are not effective against bird flu,The shortage of nurses, which is already a big
because antibiotics treat only bacterial infections, notproblem in the United States, was highlighted recently
viral infections. Antibiotics can be used to treatby Keji Fukuda of the influenza branch of the
bacterial infections that develop after viral infectionsCenters for Disease Control and Prevention (CDC).
have damaged the body, allowing bacterial infectionsAccording to Fukuda, scientists are racing to prevent
to “take over.” This can happen, forwhat could be millions of deaths from a flu pandemic,
example, when viral pneumonia turns into bacterialbut what could trip them up is the simple lack of
pneumonia. However, this did not happen in thenurses and hospital beds. He said, “No matter
1918-19 Spanish flu to any extent, nor in the 2003how good medical technology is, if we don’t
SARS pandemic, and it doesn’t appear to behave healthcare workers to care for sick people and
a significant factor in the deaths that have occurredhospital beds to put them in, it’s not a good
so far from bird flu. Hence all our sophisticatedsituation.”
antibiotics will not be of much help with bird flu.And it’s not only the limited numbers of
3. The most common cause of death from thenurses—it’s also a question of whether
1918-19 influenza pandemic, the SARS pandemic, andor not healthcare workers would come to work
from bird flu is acute respiratory distress syndromeduring a bird-flu pandemic. A recent article (b)
(ARDS). The viruses from these diseases causereported the disturbing findings of a survey of 6,000
severe damage to lungs, which results in ARDS.healthcare works in and around New York City:
Numerous treatments have been tried but generally“One assumption blown away by Hurricane
have failed. Patients with ARDS require mechanicalKatrina is that if government does nothing else, at
ventilatory support, meaning they need to be on aleast it protects people’s health and safety.
mechanical respirator. These are expensive machines,The Mailman School of Public Health at Columbia
and the supply in the United States is only slightlyUniversity in New York City set out to look at how
above demand during the normal flu season. Simplymany healthcare workers said they would show up
put, when the bird-flu pandemic strikes, therefor work, depending on the type of emergency.
won’t be enough of these machines, and soThere was some good news: 87 percent of 6,000
people who develop ARDS will not have access toworkers surveyed in 47 facilities in and around New
this potentially life-saving treatment.York said they would be able to go to work in the
4. There won’t be enough isolation rooms toevent of a mass casualty incident, and 81 percent for
place the large numbers of patients with bird flu in,an environmental disaster.
which will result in more people becoming ill throughOnly 61 percent, however, would show up for a
exposure to people with bird flu. Likewise, theresmallpox epidemic, just 48 percent during a SARS
won’t be enough of some medical equipment,epidemic and 57 percent during a ‘radiological
because of increased demand for some itemsevent.’
coupled with decreased supply—because ofThat’s a problem, isn’t it? Less than
our reliance on a global supply chain, foreignhalf of healthcare workers expect to work during a
manufacture, and just-in-time delivery. ThereSARS [or bird-flu] epidemic, and less than two-thirds
won’t be enough personal protectiveif terrorists set off a so-called dirty bomb in the
equipment (such as disposable gloves, N95 facefinancial district.
masks, gowns, face shields or goggles, head caps,‘Although we might assume that healthcare
and shoe covers), which will increase exposure andemployees have an obligation to respond to these
infection.high-impact events, our findings indicate that personal
5. During the coming pandemic, there won’tobligations, as well as concerns for their own safety,
be enough beds in hospitals for all the sick peopleplay a pivotal role in workers’ willingness to
with bird flu. Makeshift “hospitals” willreport to work,’ said Kristine Qureshi, a
have to be established outside of existing hospitals toresearcher in the epidemiology department at
care for all the ill patients.Columbia.”
6. An effective vaccine has yet to be developed, andAnd so “modern medicine,” no matter
the chances that one will be developed before ahow advanced, will clearly have difficulty dealing with
pandemic emerges are practically nonexistent. Once aa bird-flu pandemic. In a sense, the next pandemic
vaccine is developed, it will be months into thecould very well be analogous to the Hurricane Katrina
pandemic, and many people will already have becomesituation, with mass confusion, lack of resources,
ill. Because we have no natural immunity to this newvisible dead bodies, acts of cowardice and acts of
virus, we might need two immunization shots toheroism, financial disaster, panic, and every emotion
develop sufficient immunity. This makes implementingpossible—nothing like we are used to
an immunization program more difficult, andwitnessing in America; shocking.