Pharma Audit - Getting it Right the First Time

The Pharmaceutical industry is controlled byorganization, or having met with similar fate with
regulations which differ across borders. A RegulatoryEuropean Agencies, inspite of having a USFDA
Audit, although inevitable, is an ostensibly fearedclearance. The big question is how to train self, and
event, as many a fate of a Manufacturing and/orparticipants from the entire organization for an audit.
marketing license depends on its outcome. In addition,The enormous information and intelligence for this
the conformance to standards and regulations has toprocedure is best acquired by interaction - with
be reviewed periodically, by as many regulatoryexperts in the field or learning from common
agencies as diverse markets demand. An audit is amistakes. In short, a workshop, a role-play, a group
series of activities and procedures to review thediscussion, or any such activity which brings several in
adherence to pre-determined regulations andthis domain together to share their experiences is
standards. Audit in pharmaceutical industry is uniquelydesirable. Live examples and Case studies help
positioned to determine if the existing manufacturingunderstand how to "Get it right the very first time".
processes are potent enough to promise safety andEvolving market dynamics and introduction of new
standardization. An audit report, produced as aprocedures makes it necessary that manufacturing
consequence of this process, outlines the wholeprofessionals in the pharmaceutical industry - Quality
process and provides a summary of the auditand Regulatory Affairs professionals - be trained and
findings.retrained for audits. It has become necessary to
In every progressive Pharma company, it is desirableinvestigate and rectify the gap that exists in the
that the auditees be induced to develop a positiveperception and practicality of an audit. The basic aim
and professional attitude to audit. The skills of eachof audits in pharmaceuticals is to help evolve and
participant in this process of audit should be upgradedcollectively prescribe an acceptable level of safety,
and enhanced. The goal for highest possible standardsand conformance to guidance and procedures set by
cannot be viewed as being too ambitious; constantthe foremost Regulatory Agencies, USFDA, MHRA,
and fierce competition demands the "Right Firstother European Agencies, etc.
Time" Approach, each time. An accurate assessmentApplied uniformly across the industry, audit helps
can help evolve best practices, ensure safety andstandardize practices and procedures. The
promise quality. The umpteen professionals involvedpharmaceutical industry has progressively learnt not
in drug manufacturing should anticipate, accept andto deprecate audits. It is important that we all moot
acknowledge that audit is a necessary evil. It has toon this topic. The best way to prepare ourselves to
be faced with preparation and one has to adapt andcontrive on success after every audit is to attend a
evolve to participate in one.workshop or participate in discussions. The upcoming
Even so, Focused Trainings in this aspect are aconference (Prescription Pharma Support) on
neglected area. Many have been self-trained in thisregulatory audit is a focused attempt to enunciate
procedure only because they have been subjectedthe importance, procedures, preparation and conduct
to several audits in the past, and have faced successof an audit. Anybody and everybody related to
in one or more.drugs, whether in operations, research or
However, Lady Luck doesn't favour the half-preparedmanufacturing, is bound to benefit. This conference is
everytime; the quest continues as manybeing conducted at Mumbai and Hyderabad in India. It
professionals today strive to know how to prepareis clearly an inviting opportunity to learn about the
for and participate in an audit; having borne the bruntpractical perspectives of audits.
of having an FDA 483 being issued against their