| If you are finding scientific medical studies confusing, | | | | study proving Vitamin E ineffective and other citing |
| you are not alone. The main stream media daily | | | | Antioxidants (Vitamin C, E and Selenium) having no |
| menus tout breakthrough health events and | | | | effect, used forms of vitamins that are not being |
| miraculous cures and discoveries - citing scientific | | | | used in humans in one case, and no vitamins were |
| studies. Some claims are outlandish and results' | | | | used at all in the other study. But of course these |
| surprising. That's why the media is commonly | | | | facts are never reported in the media and you have |
| dropping names of celebrities and high ranking | | | | to do the sleuthing yourself. |
| university doctors to numb those who weigh such | | | | US Elite University studies, such as Harvard or Emory |
| information critically - but also as a disclaimer to | | | | are credible, right? Well, the Harvard Medical students |
| protect their networks. | | | | publicly complained about the faculties ties to drug |
| If the products or methods alluded to are of any real | | | | companies: "Harvard should be embarrassed by the F |
| or potential interest, you may want to check on the | | | | grade it recently received from the American Medical |
| credibility of the information rendered and the | | | | Student Association, a national group that rates how |
| underlying study cited. | | | | well medical schools monitor and control drug industry |
| The very first and most important piece of | | | | money." On April 9, 2009, The Boston Globe |
| information is rarely ever mentioned by the media: | | | | reported: "Dr. Robert B. Fogel, who taught at Harvard |
| who sponsored and financed the study? Studies | | | | Medical School and practiced at Brigham and Women's |
| usually deliver the results the sponsor wants, if the | | | | Hospital until 2004, said he altered numbers and |
| results are not what the sponsor expects, you'll most | | | | invented anatomic details reported in an article about |
| likely never see the result, these will be trashed or | | | | obesity and sleep apnea. The journal Sleep retracted |
| hidden from public view. So called "randomized, | | | | the article in February and the federal Office of |
| double-blind, placebo-controlled" studies sound | | | | Research Integrity concluded its investigation last |
| impressive to most people, but it still matters what | | | | month." |
| financial interest spawned the study. For example, a | | | | The FDA warrants the authenticity of studies and is |
| multi-center Canadian Universities research study, | | | | protecting you, right? Not at all, the FDA has a long |
| published March 19, 2009 in "Gut Pathogens" | | | | record of corruption and industry ties; it protects big |
| concludes, that Probiotics may be effective in easing | | | | industry not the consumer. You can read more on |
| anxiety. In this case, it was properly disclosed that | | | | this topic on line at StopFDACensorship.org, but here |
| Yakult, a Japanese producer of probiotic consumer | | | | is just one recent example: The US Government |
| products was behind the study. However, oftentimes | | | | Accountability Office, GAO, in a recent sting |
| such references are absent or hidden in footnotes of | | | | operation, was able to set up a completely fictitious |
| participating researchers biography - hoping that you | | | | medical product approval review board, using names |
| will not take the time to research every participants | | | | that were obviously false, like "Truper Dawg" and |
| industry affiliations. The National Institute of Health, | | | | "April Phuls", which happened to be diseased pet dog |
| NIH froze payments on a research grant to Emory | | | | names. In addition, the GAO invented a non existing |
| University after it learned that the scientist in charge | | | | medical product name to be investigated, which as |
| of the studies had concealed $ 2.8 million he received | | | | approved by the Independent Review Board. In the |
| from GlaxoSmithKline. A recent study carried by the | | | | case of drugs, the FDA is almost always ruling in |
| mainstream media touted that sugary soft drinks are | | | | favor of the drug companies. The Vytorin study |
| not the reason for Childhood Obesity, but the | | | | which began in 2002 found that Vytorin worked no |
| consumer had to do some research to find that the | | | | better to reduce clogged arteries than a high dose of |
| "study" was sponsored by the American Beverage | | | | a less-expensive, generically available statin alone. In |
| Association. | | | | fact, some of the Vytorin patients in that study |
| The next question is: what was the goal of the | | | | actually developed more arterial plaque than those |
| study before it began and is the outcome in line with | | | | taking Zocor alone, putting them at an even greater |
| the stated goal? It is generally accepted that for a | | | | risk of heart attacks and strokes. In spite of the fact |
| clinical trial to be effective, a study's endpoint must | | | | that the Vytorin study found that Vytorin was no |
| be set at its beginning and remain unchanged. | | | | more effective than a high dose of |
| However, some drug companies are on record to | | | | generically-available Zocor, the FDA said it was not |
| have retroactively changed the intended outcome of | | | | advising healthcare professionals to stop prescribing |
| studies in order to conceal safety issues. Merck, in a | | | | the drug. |
| joint venture with Schering-Plough completed a study | | | | Now, are the above examples just isolated cases and |
| on its Vytorin drug in April 2006, but it didn't like the | | | | the majority of clinical studies are credible? Is there |
| results, so it tried for 20 months to retro-actively | | | | any 100 percent objective studies conducted? Highly |
| alter the design of the study after the fact. But that | | | | unlikely! The fact is that practically all studies are |
| "cherry-picking" attempt outraged the medical | | | | financed directly or indirectly either by Wall Street or |
| community, so Merck just delayed the release of the | | | | a government institution. In all cases the scientists |
| study until the pressure to release it could no longer | | | | find themselves in an ethical quandary, serving their |
| be resisted. Finally, on January 14, 2008, the | | | | career goals and swing the data in favor of the |
| companies admitted that the drug doesn't work to | | | | expected outcome, or follow their inner voice and |
| their expectation. But the drug was approved by the | | | | ignore the pressure that's upon them. This pressure is |
| FDA in 2004, so the revenue was streaming during all | | | | severe when pharmaceutical studies are designed by |
| the time of procrastination. | | | | the drug companies marketing departments. |
| Next: who were the scientists named in the study; | | | | Moreover the pressure extends to the regulatory |
| did they follow through from beginning to the | | | | agency that should identify inconsistencies and flaws |
| conclusion? Particularly pharmaceutical companies have | | | | in studies: In November 2008, a group of FDA |
| a dismal record in this category, they tend to replace | | | | scientists wrote a letter to the House of |
| scientists that don't "perform" according to their | | | | Representatives "The purpose of this letter is to |
| expected outcome. The New England Journal of | | | | inform you that the scientific review process for |
| Medicine found that more than 30% of studies | | | | medical devices at the FDA has been corrupted and |
| conducted on antidepressant drugs go unpublished | | | | distorted by current FDA managers, thereby placing |
| because the outcome is not favorable for the drug | | | | the American people at risk,"..."Managers have |
| company. The Journal examined 74 studies over 23 | | | | ordered, intimidated and coerced FDA experts to |
| years and only 38 of these studies produced positive | | | | modify scientific evaluations, conclusions and |
| results for the drugs being tested. Of the 14 studies | | | | recommendations in violation of the laws, rules and |
| with unfavorable results that were published, 11 | | | | regulations, and to accept clinical and technical data |
| appeared to portray the drugs more effective than | | | | that is not scientifically valid." |
| they actually were. AstraZeneca "buried" unfavorable | | | | In conclusion, we can safely assume that media and |
| studies on its anti-psychotic drug Seroquel, because it | | | | product claims like "clinically tested", or "proven in |
| showed that it can cause diabetes. Seroquel | | | | clinical studies" are nothing more than marketing hype, |
| generated $ 4.45 billion in revenue for AstraZeneca in | | | | unless you can drill down deep enough into the study |
| 2008. | | | | to satisfy your own need and expectation of the |
| When a celebrity medical doctor puts his name on a | | | | clinical results. But in no way should you take guidance |
| study it is credible, right? At least that is what the | | | | in health related decisions based on unverified |
| media wants you to believe. But the pharmaceutical | | | | "clinically tested" claims. |
| industry is pursuing these doctors fervently - and | | | | References: |
| with lots of money and other favors. One well | | | | "NIH Freezes Grants to Emory in Secret Drug Money |
| respected individual, Dr. Scott S. Reuben turned out | | | | Scandal"; David Gutierrez; April 16, 2009; IN |
| to be a fraudster for at least 13 years during which | | | | FOODTURE WE TRUST"; Heinz Gisel; Xulon Press, |
| he fabricated data published in 21 medical journal | | | | March 2009. ISBN 978-1607912651 |
| articles. The beneficiary companies of his fabricated | | | | Drug Companies Routinely Bury Studies Showing |
| findings included Pfizer and products mentioned in his | | | | Their Drugs Don't Work"; Mike Adams; August 20, |
| articles included Celebrex, Lyrica and others. Harvard | | | | 2008. AstraZeneca Seroquel Studies 'Buried', Papers |
| University's Psychiatric Researcher Dr. Joseph | | | | Show"; Jef Feeley, Margaret Cronin Fisk; February 27, |
| Biederman received some $ 1.6 million from drug | | | | Bloomberg |
| companies, but lied about it, while he spearheaded a | | | | Key dates in Vytorin controversy"; Edward Tobin, |
| 4000% increase in pediatric bipolar disorder and put a | | | | Ransdell Pierson; March 30, 2008; Reuters |
| countless number of children on anti-psychotic drugs. | | | | FDA issues Vytorin Early Communication";Jan. 25, |
| So what are his studies for Johnson & Johnson | | | | 2008; Parker Waichman Alonso, LLP. |
| on medicines in children worth? Well, he obviously | | | | Drug Maker Told Studies Would Aid It, Papers Say"; |
| thought he owes J & J a favor, so he published | | | | Gardiner Harris, New York Times; March 19, 2009. |
| a study in the Journal of the American Medical | | | | Harvard Medical School in Ethics Quandary"; Duff |
| Association, discrediting the natural herb St. John's | | | | Wilson; New York Times, March 2, 2009. |
| Wort, stating that the herb is useless in treating | | | | Doctor's Pain Studies Were Fabricated, Hospital Says"; |
| ADHD in children. However, he used an inactive, | | | | Gardiner Harris; New York Times, March 10, 2009. |
| oxidized form of the herb in the study. Nevertheless, | | | | "Department of health and Human Services Approves |
| the mainstream media reported the doctored "study" | | | | Fictitious Medical Device Review Board Led by a |
| with headlines like: "St. John's Wort No Help in ADHD" | | | | Dead Dog"; Mike Adams; March 30, 2009. Dingell, |
| (Time, ABC News, Reuters). Since drug companies | | | | Stupak to Investigate FDA's Medical Device Approval |
| don't want you to take any natural dietary or herbal | | | | Process; Lawmakers Question Whether FDA |
| supplements, they have a vested interest in | | | | Knowingly Allowed Unsafe & Ineffective Medical |
| sponsoring such studies and every time we read | | | | Devices into U.S. Market. Committee on Energy and |
| about vitamins or minerals not being effective, we | | | | Commerce; Rep. John D. Dingell, Chairman. November |
| have to search for clues how the study was | | | | 17, 2008. |
| sponsored and conducted. For instance, a recent | | | | |