Good Manufacturing Practice – GMP Compliance Overview

For any business in the medical and pharmaceuticala book entitled Rules and Guidance for
industry, it is an essential requirement to keepPharmaceutical Manufacturers and Distributors 2007
up-to-date with the latest regulations and complythat is sometimes referred to as the ‘Orange
with Good Manufacturing Practice guidelines or GMPGuide'. This is produced for the benefit of all
compliance. GMP compliance is a means through whichpharmaceutical industry operators.
all companies in this industry are able to maintainIn many other countries, the International Conference
quality whilst proving to be effective in the biggeron Harmonisation of Technical Requirements for
business of saving people's lives through healthcareRegistration of Pharmaceuticals for Human Us (ICH)
and quality treatments.enables them to keep in line with GMP compliance
Across the world, different government and officialpractices which enable standards to be maintained
regulators enforce GMP compliance in different ways,across the world. Countries such as Australia and
but usually this is done using statutes in law. In theCanada have signed-up to this system of
US, the Food and Drug Agency enforces GMPharmonisation as well as countries from South East
compliance as part of its official remit, whilst in theAsia like Singapore. This is good news for patients
UK, the Medicines and Healthcare Productsand end-users of medical device products because it
Regulatory Agency (MHRA) acting on the Medicinesmeans safety and quality healthcare are always at
Act of 1968 has legal powers to enforce mostthe fore-front of the industry's many priorities.
aspects of GMP compliance. The MHRA also publishes